GCSE Combined Science

Biology

15 free practice questions with explanations

PassNova has 15 free GCSE Combined Science practice questions on Biology, each with a clear explanation. Practise them in the browser with instant feedback — 100% free, no sign-up, on any device. Updated for 2026.

Sample questions

Biology: example questions & answers

12 worked examples with answers and explanations below. Practise all 15 Biology questions free in the browser, with instant feedback on every answer.

  1. Which part of an animal cell controls the activities of the cell and contains the genetic material?

    • ACytoplasm
    • BCell membrane
    • CNucleus
    • DMitochondria

    Answer: The nucleus contains the chromosomes (DNA) and controls the cell's activities.

  2. Which structure is found in a plant cell but NOT in an animal cell?

    • ARibosome
    • BCell wall
    • CMitochondria
    • DCell membrane

    Answer: Plant cells have a cellulose cell wall, chloroplasts and a permanent vacuole; animal cells do not.

  3. What is the role of red blood cells?

    • AFighting infection
    • BCarrying oxygen
    • CClotting blood
    • DProducing antibodies

    Answer: Red blood cells contain haemoglobin, which binds oxygen and transports it around the body.

  4. Which process do plants use to make glucose using light energy?

    • ARespiration
    • BTranspiration
    • CPhotosynthesis
    • DDigestion

    Answer: Photosynthesis: carbon dioxide + water → glucose + oxygen, using light energy absorbed by chlorophyll.

  5. Aerobic respiration releases energy using which gas?

    • ACarbon dioxide
    • BNitrogen
    • CHydrogen
    • DOxygen

    Answer: Aerobic respiration uses oxygen: glucose + oxygen → carbon dioxide + water, releasing energy.

  6. Which enzyme breaks down starch into sugars?

    • AProtease
    • BAmylase
    • CLipase
    • DCatalase

    Answer: Amylase (a carbohydrase) digests starch into smaller sugars such as maltose.

  7. What is the name of the random change in DNA that can lead to variation?

    • AMitosis
    • BMutation
    • CMeiosis
    • DDiffusion

    Answer: A mutation is a random change in the DNA base sequence and is a source of genetic variation.

  8. In a food chain, what do the arrows represent?

    • AThe movement of animals
    • BThe direction of energy transfer
    • CThe flow of water
    • DPredator chasing prey

    Answer: Arrows in a food chain show the direction in which energy (and biomass) is transferred.

  9. Which hormone reduces blood glucose concentration?

    • AAdrenaline
    • BGlucagon
    • CInsulin
    • DTestosterone

    Answer: Insulin, released by the pancreas, causes cells to take up glucose, lowering blood glucose.

  10. Which type of cell division produces gametes (sex cells)?

    • AMitosis
    • BMeiosis
    • CBinary fission
    • DBudding

    Answer: Meiosis produces four genetically different gametes, each with half the number of chromosomes.

  11. Antibiotics are used to treat infections caused by which type of pathogen?

    • AViruses
    • BBacteria
    • CFungi only
    • DAll pathogens

    Answer: Antibiotics kill bacteria; they do not work against viruses.

  12. Which part of a plant absorbs water and mineral ions from the soil?

    • AStomata
    • BRoot hair cells
    • CXylem leaves
    • DPhloem

    Answer: Root hair cells have a large surface area to absorb water (by osmosis) and mineral ions.

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